Kyle completed his BS in Microbiology, Immunology, and Molecular Genetics at UCLA. He then completed his DDS and PhD degrees in the UCSF School of Dentistry. Kyle's PhD work was performed under the supervision of Dr. Ophir Klein and focused on the identification and characterization of oral epithelial stem cells. Kyle also completed sub-specialty training in oral and maxillofacial pathology at UCSF under the direction of Dr. Richard Jordan. He is currently an Assistant Professor in the Department of Orofacial Sciences and Director of the UCSF Oral Dysplasia Program. Kyle's research currently focuses on understanding how the immune system is altered before and after immune checkpoint inhibitor therapy in the setting of oral dysplasia (premalignant oral lesion) and head and neck cancer, especially squamous cell carcinoma.